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Publications

  1. Smith, L.M., Greenwood, H.E., Tyrrell, W.E., Edwards, R.S., de Santis, V., Baark, F., Firth, G., Tanc, M., Terry, S.Y.A., Herrmann, A., Southworth, R., Witney, T.H. The chicken chorioallantoic membrane as a low-cost, high-throughput model for cancer imaging. npj Imaging, 2023, 1, 1, DOI: 10.1038/s44303-023-00001-3.
  2. Read, M., Brookes, K., Zha, L., Manivannan, S., Kim, J., Kocbiyik, M., Fletcher, A., Gorvin, C., Firth, G., Fruhwirth, G., Nicola, J., Jhiang, S., Ringel, M., Campbell, M., Sunassee, K., Blower, P.J., Boelaert, K., Nieto, H., Smith, V., McCabe, C. Combined Vorinostat and Chloroquine Inhibit Sodium Iodide Symporter Endocytosis and Enhance Radionuclide Uptake In Vivo. Clinical Cancer Research, 2023, just accepted.
  3. Imberti, C, Lok, J., Coverdale, J.P.C., Carter, O.W.L., Fry, M.E., Capper, M., Kim, J., Firth, G., Blower, P.J., Sadler, P.J. Radiometal-labelled photoactivatable Pt(IV) anticancer complex for theranostic phototherapy. Inorganic Chemistry, 2023, DOI: 10.1021/acs.inorgchem.3c02245.
  4. Coupland, C.A., Naylor-Adamson, L., Booth, Z., Price, T.W., Firth, G., Avery, M., Ahmed, Y., Stasiuk, G.J., Calaminus, S.D.J. Platelet Zinc status regulates prostaglandin-induced signaling altering thrombus formation. Journal of Thrombosis and Haemostasis, 2023, DOI: 10.1016/j.jtha.2023.05.008.
  5. Firth, G.,* Georgiadou, E., Griffiths, A., Amrahli, M., Kim, J., Yu, Z., Parker, D., Hu, M., Stewart, T.J., Leclerc, I., Okamoto, H., Kleiner, S., Blower,P.J., Rutter, G.A.* Impact of an SLC30A8 loss-of-function variant on the pancreatic distribution of zinc and manganese, Frontiers in Endocrinology, 2023, 14, DOI: 10.3389/fendo.2023.1171933. *Corresponding author.
  6. Nuttall, R.E., Pham, T.T., Chadwick, A.C., Hungnes, I.N., Firth, G., Martin A. Heckenast, M.A., Sparkes, H.A., M. Galan, C., Ma, M.T., Pringle, P.G. A Versatile Chelator Platform for Technetium-99m and Rhenium-188 Radiolabeling of Biomolecules. Inorganic Chemistry, 2023, DOI: 10.1021/acs.inorgchem.2c04008.
  7. Firth, G., Yu, Z., Bartnicka, J.J., Parker, D., Kim, J., Sunassee, K., Greenwood, H.E., Al-salamee F., Jauregui-Osoro, M., Di Pietro, A., Guzman, J., Blower, P.J. Imaging zinc trafficking in vivo with 62Zn-PET, Oxford Metallomics, 2022, 14, mfac076.
  8. Frei, A., Rigby, A., Yue, T.T.C., Firth, G., Michelle T. Ma, M.T., Long, N.J. To chelate thallium(I) – synthesis and evaluation of Kryptofix-based chelators for 201Tl, Dalton Transactions, 2022, 51, 9039-9048.
  9. Rigby, A., Firth, G., Rivas, C., Pham, T., Kim, J., Phanopoulos, A., Wharton, L., Ingham, A., Li, L., Ma, M., Orvig, C., Blower, P.J., Terry, S.Y.A., Abbate, V. Towards bifunctional chelators for thallium-201 for use in nuclear medicine, Bioconjugate Chemistry, 2022, 33, 1422-1436.
  10. Firth, G.,* Blower, J., Bartnicka, J., Mishra, A., Michaels, A., Rigby, A., Darwesh, A., Al-Salemee, F.A.I., Osytek, K., Blower, P.J. Non-invasive radionuclide imaging of trace metal trafficking in health and disease: “PET metallomics”, RSC Chemical Biology, 2022, 3, 495-518. *Corresponding author, front cover.
  11. Greenwood, H.E., Edwards, R., Koglin, N., Berndt, M., Baarke, F., Kim, J., Firth, G., Mueller, A., Witney, T.H. Radiotracer stereochemistry affects substrate affinity and kinetics for improved imaging of system xC- in tumors, Theranostics, 2022, 12, 1921-1936.
  12. Farleigh, M., Pham, T.T., Yu, Z., Kim, J., Sunassee, K., Firth, G., Forte, N., Chudasama, V., Baker, J.R., Long, N.J., Rivas, C., Ma, M.T. New bifunctional chelators incorporating dibromomaleimide groups for radiolabeling of antibodies with PET imaging radioisotopes, Bioconjugate Chemistry, 2021, 32, 1214–1222.
  13. Bartnicka, J.J., Al-salemee, F., Firth, G., Maret, W., Blower, P.J. L-Cysteine-mediated modulation of copper trafficking in prostate cancer cells: an in vitro and in vivo investigation with 64Cu and 64Cu-PET, Metallomics, 2020, 12, 1508-1520. Front cover.
  14. Mota, F., Ordonez, A.A., Firth, G., Ruiz-Bedoya, C.A., Ma, M.T., Jain, S.K, Radiotracer Development for Bacterial Imaging. J. Med. Chem. 2020, 63, 1964-1977.
  15. Firth, G., Price, T., Eling, C.J., Kinnon, M., Long, J.J., Sturge, J., Stasiuk, G.J. A 18F radiolabelled Zn(II) sensing fluorescent probe. Chem. Commun., 2018, 54, 3227-3230.
  16. Eling C.J., Price T.W., Marshall A.R.L., Viscomi F.N., Robinson, P., Firth, G., Adawi, A.M., Bouillard, J-S.G., Stasiuk, G.J. A Dual-Modal SERS/Fluorescence Gold Nanoparticle Probe for Mitochondrial Imaging. Chempluschem. 2017; 82, 674-680.